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(Tetratetracontapeptide–46 Amino Acids)

Brief Summary

FOXO4-DRI is a peptide research compound studied in laboratory settings for its relevance to transcription factor related pathway investigation, cellular regulation mechanisms, and controlled sequence based analysis. It is commonly examined in structured research models focused on peptide interaction patterns, biochemical response pathways, and comparative mechanism studies under defined laboratory conditions. Within scientific supply catalogues, FOXO4-DRI is valued for in vitro and preclinical research involving pathway observation, marker evaluation, and analytical peptide investigation.

Product Overview

FOXO4 Peptide is a sequence specific peptide compound developed for research into forkhead box O transcription factor signalling pathways. It is designed to interact with molecular processes associated with FOXO4 mediated regulation of cell survival, oxidative stress response, and cellular homeostasis. The peptide is produced using controlled laboratory processes to ensure sequence fidelity, purity, and batch reproducibility. Its molecular composition allows targeted interaction with intracellular regulatory complexes involved in transcriptional control. Supplied in lyophilised format, the compound demonstrates favourable stability characteristics under appropriate laboratory storage conditions, supporting extended research programmes focused on senescence modulation, transcription factor activity, and peptide driven regulation of cell fate decisions.

Scientific Background

Scientific research into FOXO4 Peptide centres on its relevance to cellular senescence and stress response pathways governed by FOXO family transcription factors. FOXO4 plays a key role in regulating gene expression linked to cell cycle arrest, DNA repair processes, and resistance to oxidative stress. Peptide based modulation of these pathways allows researchers to study senescent cell persistence, apoptosis resistance mechanisms, and transcriptional control dynamics. Investigations explore interactions with p53 signalling, nuclear localisation behaviour, and downstream gene regulatory networks. The predictable activity profile of the peptide enables controlled examination of cellular ageing processes, signalling thresholds, and regulatory feedback mechanisms within in vitro experimental systems.

Research Applications

In laboratory research environments, FOXO4 Peptide is utilised in in vitro models examining cellular senescence, transcription factor regulation, and stress response signalling. It is applied in studies investigating senescent cell survival mechanisms, apoptosis sensitivity, and gene expression modulation. Additional applications include cellular ageing research, oxidative stress assays, and peptide based exploration of transcriptional control networks. The compound is also employed in comparative studies assessing regulatory peptide influence on senescence pathways and cell fate determination. Its reproducible activity supports use as a reference compound in ageing research.

Technical Specification

• Contents: 10mg FOX04
• Form: Lyophilized powder
• Purity: >99% (HPLC Verified)
• Storage: Store between 2°C and 8°C
• Molecular Formula: C₂₂₈H₃₈₈N₈₆O₆₄
• Sequence: D-(Leu-Thr-Leu-Arg-Lys-Glu-Pro-Glu-Glu-Tyr-Leu-Leu-Gln-Asn-Gln-Arg-Arg-Arg)
• Peptide Length: 18 Amino-Acids
• pH Range: 5.6-7.2

Note: Reconstitute with Bacteriostatic (BAC) Water 10ml for best results.

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Disclaimer

For research purposes only. Not for human consumption