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Batch Documentation-Identity & Purity Control

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Research Compound Summary

RAD-150 is studied as an androgen receptor ligand used to examine androgen receptor signalling in controlled experimental systems. The androgen receptor is a nuclear hormone receptor that, when engaged by a ligand, can translocate to the nucleus, interact with androgen response elements on DNA, and recruit coactivator or corepressor proteins that reshape transcriptional output. In AR expressing cell models, RAD-150 is used to assess ligand driven transcriptional activity and compare signalling strength, duration, and selectivity against other reference ligands. Typical approaches include receptor binding and competition assays, AR reporter systems, nuclear localisation imaging, and chromatin occupancy studies, paired with transcriptional readouts such as KLK3, FKBP5, and TMPRSS2, alongside broader RNA sequencing panels. Publicly available technical detail on RAD-150 is more limited than for some better characterised AR ligands, so it is generally described within androgen receptor modulation research rather than as a deeply established reference compound.
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Technical Specification

Synonyms: RAD150, RAD-150, TLB-150 Benzoate, TLB 150 Benzoate
Chemical Class: Selective androgen receptor modulator
Long Chemical Name: (IUPAC style listing): 4-[[(1R,2S)-2-(benzoyloxy)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]propyl]amino]-2-chloro-3-methyl-benzonitrile
Molecular Weight: 497.93 g/mol
Formula: C27H20ClN5O3
Contains: 9.99% TLB-150 (RAD-150)
CAS/Batch: OS001-03-2026
Storage: Store between 10-15°C
Purity: 99.2% (documented under batch specific testing)

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Disclaimer

For research purposes only. Not for human consumption