PT-141 10mg
(Bremelanotide)

Premium Grade | UK Supply

(Heptapeptide, 7 amino acids)

 

Brief Summery

PT-141 (Heptapeptide–7 Amino Acids) is a cyclic melanocortin research peptide studied for its interaction with melanocortin receptor pathways in controlled laboratory settings. Its structure and receptor binding profile make it of interest in peptide science focused on neuropeptide signalling, receptor selectivity, and central pathway mapping. In preclinical and in vitro research, PT-141 is often discussed in relation to melanocortin system activity, signalling cascade observation, and comparative receptor response studies. Its compact sequence and targeted pathway relevance have made it a recognised compound in experimental work exploring peptide driven communication between receptor systems and broader neuroendocrine signalling models.

 

Product Overview

PT-141, also known as Bremelanotide, is a synthetic cyclic peptide derived from alpha melanocyte stimulating hormone (α-MSH) and is extensively studied for its role in melanocortin receptor signalling within the central nervous system. Unlike endocrine peptides that act through peripheral hormone pathways, PT-141 is primarily researched for its direct interaction with melanocortin receptors involved in neurochemical communication and central signalling mechanisms. In laboratory and research environments, PT-141 is utilised to investigate melanocortin receptor activation, neuropeptide signalling dynamics, and central nervous system pathway modulation. Its defined cyclic structure and receptor specificity make it a valuable compound for studying targeted neurochemical signalling processes. PT-141’s unique origin and well characterised receptor interactions position it as an important peptide in advanced neurobiology and melanocortin pathway research. 
(Recommend, Reconstitute with-Acetic Acid)

Scientific Background

PT-141 is structurally based on a modified α-MSH peptide sequence and functions as an agonist at melanocortin receptors, particularly MC3R and MC4R. Receptor activation initiates intracellular signalling cascades involving cyclic AMP and downstream transcriptional regulation, allowing researchers to examine melanocortin driven neural signalling independent of peripheral hormonal systems. At the molecular level, PT-141 is studied for its ability to influence neurotransmitter release, neuronal excitability, and central signalling network integration. These mechanisms provide insight into how melanocortin peptides regulate complex neural communication systems and behavioural signalling pathways. The cyclic structure of PT-141 enhances receptor binding stability and resistance to enzymatic degradation, making it suitable for controlled experimental evaluation of melanocortin receptor dynamics and signalling persistence. 

 

Research Applications

PT-141 is extensively researched in neuroscience, neuroendocrinology, and molecular signalling science, particularly in studies examining melanocortin receptor biology and central nervous system communication pathways. Researchers utilise PT-141 to explore receptor specific signalling, neuropeptide mediated communication, and intracellular response patterns in controlled experimental models. In behavioural and cognitive research frameworks, PT-141 is studied for its role in central signalling modulation and neurotransmitter pathway interaction. These investigations contribute to a broader understanding of melanocortin system function and neural network regulation. Additionally, PT-141 is employed in advanced research focused on receptor pharmacology, neuropeptide structure function relationships, and central signalling pathway analysis. Its specificity and extensive documentation make PT-141 a key compound in melanocortin and neuropeptide research.
(Read more about PT-141 in our Article)

 

Technical Specifications

• Contents: 10mg PT-141
• Form: Lyophilized powder
• Purity: >99% (HPLC Verified)
• Molecular Formula: C₅₀H₆₈N₁₄O₁₀
• Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH
• Peptide Length: 7 Amino-Acids
• pH Range: 4.0-8.0
• Storage: Store between 1°C and 3°C

Note: Reconstitute with 50% Bacteriostatic (BAC) water and 50% Acetic Acid for best results.

Related Research Compounds

Kisspeptine 10mg
5-Amino-1mq 5mg
KVP 10mg

Disclaimer

For research purposes only, Not for human consumption.